Parkinson's Disease Research
Hammer Neuromodulation Lab @ UPenn
As a Research Intern at the University of Pennsylvania's Hammer Neuromodulation Laboratory, I analyzed local field potential (LFP) recordings from DBS-implanted Parkinson's patients to identify stimulation-entrained gamma oscillations as candidate biomarkers for adaptive deep brain stimulation.
This research focuses on developing more precise and personalized treatment approaches for Parkinson's disease through advanced neuromodulation techniques and biomarker identification.
Key Contributions
- • Analyzed complex neural signal data from DBS-implanted patients
- • Identified gamma oscillation patterns as potential biomarkers
- • Contributed to adaptive deep brain stimulation research
- • Collaborated with interdisciplinary research team
Research Impact
This research contributes to the advancement of personalized medicine in Parkinson's disease treatment. By identifying gamma oscillations as potential biomarkers, this work could enable more precise and adaptive deep brain stimulation protocols, potentially improving patient outcomes while reducing side effects.
The findings have implications for developing closed-loop DBS systems that can automatically adjust stimulation parameters based on real-time neural feedback, representing a significant step toward truly personalized neuromodulation therapy for movement disorders.