Microfluidic Chip Design

Project Overview

Working as a Laboratory Assistant at the Trauma and Transfusion Medicine Research Center (Shea Lab), I develop and optimize microfluidic chip models to simulate vascularized environments. This research enables in-depth study of endothelial cell behavior and dysfunction under traumatic injury and inflammation conditions.

Key Contributions

• •Design and fabrication of microfluidic devices that replicate physiological vascular environments
• •Optimization of chip parameters to study endothelial cell responses to trauma and inflammation
• •Development of protocols for cell culture and analysis within microfluidic systems
• •Investigation of cellular dysfunction mechanisms in traumatic injury scenarios

Research Impact

This work contributes to understanding how traumatic injuries affect vascular function at the cellular level, potentially leading to improved treatment strategies for trauma patients. The microfluidic models provide a controlled environment to study complex biological processes that are difficult to observe in traditional cell culture systems.